Microsoft published Security Advisory (968272) on Tuesday and recommends using the Microsoft Office Isolated Conversion Environment (MOICE) as a workaround. High risk "targets" may want to consider this as standard operating procedure.
Adobe's mitigation steps involve disabling JavaScript. However, see discussion here as well.
Adobe's steps are as follows:
1. Launch Acrobat or Adobe Reader. 2. Select Edit>Preferences 3. Select the JavaScript Category 4. Uncheck the "Enable Acrobat JavaScript" option 5. Click OK
I'd show you a screenshot of the options, only I don't have Adobe Reader installed.
I find it a bit confusing how commonplace Adobe Reader has become. For some reason everybody seems to be using it for reading PDF files. Even though there are plenty of free alternatives. And the alternatives are much smaller and faster. And start up in under a minute.
From my point of view, Adobe Reader has become the new IE. For security reasons, avoid it if you can.